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Poppers. Not only are they a staple of disco dance floors, sex shops, and — more recently — gay internet memes, but openly queer pop star Troye Sivan recently placed them front and center in the mainstream by openly paying homage to them with his summer 2023 smash hit “Rush,” a song title that not-so-coincidentally is the name of a beloved brand of poppers.

But what exactly are poppers? What risks do they present users? And how can these risks be mitigated? I spoke with DAP Health Chief of Community Health C.J. Tobe and asked all of the tough questions.

What are poppers?

Basically, “poppers” is the casual name for a liquid inhalant. Most people are probably familiar with using poppers on the dance floors in the ’60s, ’70s, and ’80s. Then they transitioned into being extremely useful during sex. There are four different chemicals that can make up poppers [amyl nitrite, isopropyl nitrite, butyl nitrite, and pentyl nitrite].

Why do people do poppers?

Because they feel good. For many people, they make sex even more enjoyable. People who may have sex anxiety or need “liquid courage” (like we talk about with alcohol) may find poppers helpful and relaxing.

What actually happens to your body when you use poppers?

When you inhale poppers, your blood vessels are going to expand, and it’s then going to increase the blood flow and oxygen level within your veins. So that’s what makes it feel euphoric. It’s like a rush, essentially. But while all that is happening, it’s also gonna decrease your blood pressure. Obviously, people with heart conditions are definitely advised to be very, very cautious.

Speaking of being cautious, if one were to do poppers, is there any way to do them more safely?

Probably don’t use them alone, because using them will increase your blood flow, which will then lower your blood pressure. Just in the event that you do pass out, you don’t want to be alone. So … poppers and porn? Not the best idea.

A lot of people who use poppers, especially during sex, are also taking erectile dysfunction medicine. That’s an added risk for decreasing blood pressure, which can eventually cause someone to pass out — potentially even vomit and die as well.

Are there any other risks to consider?

Generally, some research shows that using poppers can put you at a higher risk of getting an STI, including HIV. Everyone should regularly be screened for STIs and HIV, and we also recommend considering being on PrEP and/or DoxyPEP.

While poppers may make sex more enjoyable, they’ll also give you a high, where you become dizzy and you don’t know exactly what’s going on. You could put yourself in a vulnerable position, where someone can take advantage of you. It just makes you less aware of your surroundings, which also could increase the possibility of something negative happening.

What about the dreaded, so-called “poppers nose,” (aka chemical burns in one’s nostrils)?

My advice to prevent this would be to inhale through your mouth. Just like a cigarette [without putting your lips on the bottle]. It bypasses actually going up through your nostrils and won’t give you a headache. I learned that from an expert who reps a national poppers brand.

Can poppers be addictive?

There’s little research to prove or disprove the addictive effects. However, from a cognitive behavioral perspective, anything can become addictive, especially agents that produce pleasure, promote escapism, or assist in numbing. Poppers create a sense of euphoria, so someone can very well become accustomed to this experience while having sex and require it to allow for a full sense of pleasure due to the association. However, ultimately, physiological dependence? No.

I would add to this: It is very much recognized as a relapse trigger for those in recovery. The erotic experience can create what is referred to as “euphoric recall,” which directly sets off a chain of thought and behavior patterns. So related to addiction, it is definitely high-risk.

How come poppers are sometimes sold with code names like VCR cleaner or tar remover? Why the code names? Are poppers legal?

From my last understanding, it’s illegal to consume nitrite, as well as some of the things that go into poppers for recreational use. So, when you would go into a store, they’re sometimes number coded: “I want number two, I want number eight, I want the yellow or the red.” Legally, we’re not really allowed to state that you were there to get poppers in a sex shop or store. It’s legal to sell it, but it should not be used recreationally.

Anything else to add?

I know this is going to sound very corny but talk to your doctor! I know it’s so basic to people. We can Google all day… But, ultimately, just tell your doctor you want to do poppers. Or let them know you’ve been doing poppers for 10 years. They can look at your medication list for any potential risks and ensure you are receiving sexual wellness support. I think the more education and knowledge we have around health matters, the better. Even if your doctor may not be culturally competent on poppers, you can start that conversation to make them curious. Get them educated on poppers so they can help guide and educate some of their other patients. And I just have to add, here at DAP Health, we are very culturally competent. We all know all about poppers. And we provide service without stigma, shame, or judgment. You can always ask your DAP Health provider anything.

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